Platelet Rich Fibrin and Periodontal Tissue Regeneration

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Platelet Rich Fibrin in Periodontal Regeneration

Periodontitis is a chronic bacterial infection resulting in destruction of the supporting structures of the teeth. Regeneration of the lost tissues has faced difficulties primarily due to the lack of support during the intricate healing processes. A surgical additive which can 'jump start' the healing process to a more predictable regenerative process is always on the wish list of any periodont...

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Design and Fabrication of a Novel Transplant Combined with Human Bone Marrow Mesenchymal Stem Cells and Platelet-rich Fibrin: New Horizons for Periodontal Tissue Regeneration after Dental Trauma

Avulsed teeth that are replanted dried are more prone to loss. Recent tissue engineering studies focus onfabrication of various cell delivery systems to improve the overall prognosis of such teeth. To evaluate this newcell transplant method, we initially aimed at designing of PRF scaffold and determining BMMSCs viabilityand function on the fabricated scaffold. To test this concept in-vitro, hum...

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Design and Fabrication of a Novel Transplant Combined with Human Bone Marrow Mesenchymal Stem Cells and Platelet-rich Fibrin: New Horizons for Periodontal Tissue Regeneration after Dental Trauma

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In the present study we have determined the suitability of platelet-rich fibrin (PRF) as a complex scaffold for periodontal tissue regeneration. Replacing PRF with its major component fibrin increased mineralization in alveolar bone progenitors when compared to periodontal progenitors, suggesting that fibrin played a substantial role in PRF-induced osteogenic lineage differentiation. Moreover, ...

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ژورنال

عنوان ژورنال: Advances in Dentistry & Oral Health

سال: 2017

ISSN: 2472-6389

DOI: 10.19080/adoh.2017.04.555649